cophesim: a comprehensive phenotype simulator for testing
ثبت نشده
چکیده
Simulation is important in evaluating novel methods when input data is not easily obtainable or specific assumptions are needed. We present , a cophesim software to add the phenotype to generated genotype data prepared with a genetic simulator. The output of can be used as a direct input for cophesim different genome wide association study tools. is available from cophesim . https://bitbucket.org/izhbannikov/cophesim Ilya Y. Zhbannikov ( ), Konstantin G. Arbeev ( ) Corresponding authors: [email protected] [email protected] : Conceptualization, Investigation, Methodology, Project Administration, Software, Validation, Visualization, Writing – Author roles: Zhbannikov IY Original Draft Preparation, Writing – Review & Editing; : Resources, Supervision, Writing – Review & Editing; : Resources, Arbeev KG Yashin AI Supervision, Writing – Review & Editing Competing interests: No competing interests were disclosed. Zhbannikov IY, Arbeev KG and Yashin AI. How to cite this article: cophesim: a comprehensive phenotype simulator for testing novel 2017, :1294 (doi: ) association methods [version 1; referees: awaiting peer review] F1000Research 6 10.12688/f1000research.11968.1 © 2017 Zhbannikov IY . This is an open access article distributed under the terms of the , Copyright: et al Creative Commons Attribution Licence which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. This work was supported by the National Institute on Aging of the National Institutes of Health (NIA/NIH) under award numbers Grant information: P01AG043352, R01AG046860, and P30AG034424 The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. 01 Aug 2017, :1294 (doi: ) First published: 6 10.12688/f1000research.11968.1 Referee Status: AWAITING PEER REVIEW 01 Aug 2017, :1294 (doi: ) First published: 6 10.12688/f1000research.11968.1 01 Aug 2017, :1294 (doi: ) Latest published: 6 10.12688/f1000research.11968.1 v1 Page 1 of 6 F1000Research 2017, 6:1294 Last updated: 01 AUG 2017
منابع مشابه
cophesim: a comprehensive phenotype simulator for testing novel association methods
Simulation is important in evaluating novel methods when input data is not easily obtainable or specific assumptions are needed. We present cophesim, a software to add the phenotype to generated genotype data prepared with a genetic simulator. The output of cophesim can be used as a direct input for different genome wide association study tools. cophesim is available from https://bitbucket.org/...
متن کاملcophesim: A comprehensive phenotype simulator for testing
Simulation is important in evaluating novel methods when input data is not easily obtainable or specific assumptions are needed. We present , a cophesim software to add the phenotype to generated genotype data prepared with a genetic simulator. The output of can be used as a direct input for cophesim different genome wide association study tools. is available from cophesim . https://bitbucket.o...
متن کاملIdentification of First Patient with Rh null Phenotype in Southeast Iran
Background and Aims: Rhnull, with an estimated incidence of one per 6,000,000 individuals, is an extremely rare disorder with an autosomal recessive pattern of inheritance that is more common in societies with a high rate of consanguinity. Materials and Methods: In this study, we report the first case with Rhnull, a blood group phenotype in southeast Iran, which was diagnosed during pretransf...
متن کاملSoft Tissue Modeling Using ANFIS for Training Diagnosis of Breast Cancer in Haptic Simulator
Soft tissue modeling for the creation of a haptic simulator for training medical skills has been the focus of many attempts up to now. In soft tissue modeling the most important parameter considered is its being real-time, as well as its accuracy and sensitivity. In this paper, ANFIS approach is used to present a nonlinear model for soft tissue. The required data for training the neuro-fuzzy mo...
متن کاملDistance protection closed-loop testing using RTDS
This paper presents a distance protection test procedure by applying the Real-Time Digital Simulator (RTDS) of a power system. RTDS is a tool to design, develop, and test power-system protection. The RTDS enables real-time computation of electromagnetic phenomena with a calculation time step of even 50μs. The hardware allows the import and export of many signals from the simulator to an ext...
متن کامل